Universal ICU Decolonization: An Enhanced Protocol


Universal ICU Decolonization: An Enhanced Protocol


The Universal Intensive Care Unit (ICU) Decolonization Protocol combines a comprehensive implementation readiness assessment with scientific rationale and training tools for implementation of a universal decolonization strategy to reduce methicillin-resistant Staphylococcus aureus (MRSA) and bloodstream infections in adults. It is intended for use by acute care hospitals that serve critically ill adults in dedicated ICUs. This enhanced protocol provides a scientific foundation for hospital leaders of critical care and infection prevention programs to assess the value of and need for this intervention in their hospital for decisionmaking purposes. It also provides materials and steps for implementation.

This resource includes the following items:

  • Information to help prepare for launch, as well as a flowchart
  • Information on decisionmaking and implementation readiness
  • An overview statement and information on universal decolonization in adult ICUs
  • A universal ICU decolonization nursing protocol
  • Training and educational materials
  • Protocol skills assessment
  • Product safety information


Harvard Pilgrim Health Care; Hospital Corporation of America; University of California Irvine

Funding Sources:

Agency for Healthcare Research and Quality


Release Date: 2013
Original Summary: November 2013
Last Updated: 12/04/13

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