Newborn Screening ACTion (ACT) Sheets and Confirmatory Algorithms


Newborn Screening ACTion (ACT) Sheets and Confirmatory Algorithms


The Newborn Screening ACTion (ACT) sheets and Confirmatory Algorithms are educational resources for physicians. The ACT sheet describes the short-term actions a health professional should follow in communicating with the family and determining the appropriate steps in the followup of the infant who has screened positive. The algorithms present an overview of the basic steps involved in determining the final diagnosis in the infant.

ACT sheets and algorithms include the following condition groups:

  • Endocrine disorders
  • Hemoglobin disorders
  • Genetic disorders
  • Metabolic – galactosemias
  • Metabolic – fatty acid oxidation disorders
  • Metabolic – organic acidemias
  • Metabolic – amino acidemias


American College of Medical Genetics

Funding Sources:

Maternal and Child Health Bureau-Health Resources and Services Administration


Release Date: 2006
Original Summary: September 2008
Last Updated: 08/13/14

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